Three species of terminalia are used in medicine

Terminalia is a tree. Three species of terminalia are used in medicine, particularly in Ayurvedic medicine. These species are Terminalia arjuna, Terminalia bellirica and Terminalia chebula.

Terminalia is most commonly used for heart disease, including heart failure and chest pain. It is also used for diabetes, high cholesterol, and many other conditions, but there is no solid scientific evidence to support these uses.

How it works ?
Terminalia contains ingredients that help stimulate the heart. It might also help the heart by lowering cholesterol and blood pressure.

Uses and Effectiveness

May be effective for
Chest pain (angina). Some research shows that taking Terminalia by mouth with conventional medication improves symptoms in people with chest pain after a heart attack. Other research shows that taking Terminalia by mouth improves symptoms and reduces the need for chest pain medication in people with long-term chest pain.
There is interest in using terminalia for several other purposes, but there is not enough reliable information to say whether it might be useful.

Side effects
When taken by mouth: Terminalia arjuna is POSSIBLY SAFE when taken by mouth for 3 months or less. But do not use Terminalia arjuna without medical supervision. It could affect your heart.

There is not enough reliable information to know if other Terminalia species, including Terminalia bellirica or Terminalia chebula, are safe. It is best to avoid using it until more is known.

Special Precautions and Warnings
When taken by mouth: Terminalia arjuna is POSSIBLY SAFE when taken by mouth for 3 months or less. But do not use Terminalia arjuna without medical supervision. It could affect your heart.

There is not enough reliable information to know if other Terminalia species, including Terminalia bellirica or Terminalia chebula, are safe. It is best to avoid using it until more is known. Pregnancy: There is evidence that Terminalia arjuna is POSSIBLY HARMFUL during pregnancy. There is not enough reliable information to know if other Terminalia species can be used safely during pregnancy. Be careful and avoid using Terminalia species.

Breast-feeding: There is not enough reliable information to know whether Terminalia can be used safely while breast-feeding. Be careful and avoid using it.

Bleeding Disorders: Terminalia can slow blood clotting. This could increase the risk of bruising and bleeding in people with bleeding disorders.

Diabetes: Terminalia may lower blood sugar levels. Your diabetes medications may need to be adjusted by your healthcare provider.

Surgery: Terminalia can interfere with blood sugar control and increase the risk of bleeding during surgery. Stop taking Terminalia at least 2 weeks before scheduled surgery.

interactions?
Moderate interaction
Be careful with this combination

Medicines for diabetes (antidiabetic medicines) interact with TERMINALIA
Terminalia might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking Terminalia with diabetes medications may cause your blood sugar levels to drop too low. But more evidence is needed to know if this interaction is a big concern. Monitor your blood sugar carefully.

Some drugs used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol ), tolbutamide (Orinase),

Drugs that slow blood clotting (anticoagulants/antiplatelet drugs) interact with TERMINALIA
Terminalia might slow blood clotting. Taking Terminalia with medications that also slow clotting may increase the risk of bruising and bleeding.

Some drugs that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin) and others.

Drugs modified by the liver (cytochrome P450 2C9 (CYP2C9) substrates) interact with TERMINALIA
Some drugs are changed and broken down by the liver. Some research suggests that Terminalia arjuna may decrease how quickly the liver breaks down certain drugs, although other Terminalia species may not have this effect. Taking Terminalia with certain medications that are broken down by the liver may alter the effects and side effects of certain medications.

Some liver-modified drugs include amitriptyline (Elavil), diazepam (Valium), zileuton (Zyflo), celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin) and others .

Drugs modified by the liver (cytochrome P450 2D6 (CYP2D6) substrates) interact with TERMINALIA
Some drugs are changed and broken down by the liver. Some research suggests that Terminalia arjuna may decrease how quickly the liver breaks down certain drugs, although other Terminalia species may not have this effect. Taking Terminalia with certain medications that are broken down by the liver may alter the effects and side effects of certain medications.
Some liver-modified drugs include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine ( Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel) and others.

Drugs modified by the liver (cytochrome P450 3A4 (CYP3A4) substrates) interact with TERMINALIA
Some drugs are changed and broken down by the liver. Some research suggests that Terminalia arjuna may decrease how quickly the liver breaks down certain drugs, although other Terminalia species may not have this effect. Taking Terminalia with certain medications that are broken down by the liver may alter the effects and side effects of certain medications.
Some liver-modified drugs include lovastatin (Mevacor), clarithromycin (Biaxin), cyclosporine (Neoral, Sandimmune), diltiazem (Cardizem), estrogens, indinavir (Crixivan), triazolam (Halcion), and many others.

Omeprazole (Prilosec) interacts with TERMINALIA
The body breaks down omeprazole to get rid of it. Terminalia chebula might decrease how quickly the body breaks down omeprazole. Taking Terminalia chebula with omeprazole might increase the effects and side effects of omeprazole.

Chlorzoxazone (Parafon Forte, Paraflex) interacts with TERMINALIA
The body breaks down chlorzoxazone to get rid of it. Terminalia chebula might decrease how quickly the body breaks down chlorzoxazone. Taking Terminalia with chlorzoxazone could increase the effects and side effects of chlorzoxazone.

Dosage
The following doses have been studied in scientific research:

BY THE MOUTH:
For chest pain (angina pectoris): 500 mg Terminalia arjuna bark powder has been taken three times daily with conventional treatment for chest pain for up to 3 months.

Leave a Reply

Your email address will not be published.